Articles
Personalized Pipeline: GenomeWeb
June 2011
By uniting the cancer research community within a traditional grid infrastructure, caBIG demonstrates one scenario in which biomedical data can be securely shared by both organizations and individuals with the type of connectivity that personalized medicine will require.
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Journal of the National Cancer Institute: Big Databases: Outcomes Research Begins To Yield Results
In the February 24, 2010 edition of the Journal of the National Cancer Institute, Merrill Goozner discusses the progression of outcomes databases and their ability to play a role in comparative effectiveness research within the field of oncology. Citing initiatives launched by the National Comprehensive Cancer Network and the American Society of Clinical Oncology, Goozner mentions that the NCI has invested $20 million to set up caBIG® to collect and use all kinds of data, including outcomes data. Although questions remain about the willingness and ability of oncologists to participate in generating outcomes data that comparative-effectiveness researchers need, signs of progress most certainly exist.
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Journal of the National Cancer Institute: In Silico Research: Pushing It Into the Mainstream
In the February 24, 2010 edition of the Journal of the National Cancer Institute, Karyn Hede discusses the ability of the NCI to make terabytes of biological data accessible through caBIG®. The caBIG® tools have been deployed at 56 NCI-designated cancer centers, as well as 16 community cancer partners in the effort to move bioinformatics-driven, or in silico, research projects into the larger research community. The article features commentary from Dr. Ken Buetow who discusses what exactly the NCI hopes to accomplish with its funding of these in silico centers.
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BIO Show Daily: Today's Research is Tomorrow's Care
In the May 20, 2009 edition of the BIO Show Daily (Published by The Scientist for the 2009 BIO International Convention), Dr. Ken Buetow introduces the Cancer Knowledge Cloud—a caGrid-supported platform enabling remote access to data, analytical tools, and computing power—and describes how initiatives, such as the BIG Health Consortium™ are digitally connecting the biomedical ecosystem.
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The Scientist: Heading for the BIG Time
In the April 2008 issue of The Scientist, Dr. Ken Buetow discusses how caBIG® was developed in response to an urgent need in cancer research to expedite the transformation of scientific findings into clinical solutions. He describes how caBIG® facilitates the flow of information across institutions, departments, and disciplines to enable large-scale collaborative research; and explains how this greater connectivity will help the clinical and basic research communities achieve the promise of personalized medicine. View PDF
